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English: Example: Rituxan® (rituximab)

Rituxan® (rituximab) isi a good example of a monoclonal antibody that can activate the immune system to attack a cancer cell. It binds to a surface protein, called CD20, located on mature B lymphocytes (B cells). Once bound, the antibody activates the body's immune system, which then attacks the cancer cells. Rituxan® (rituximab) may also make cells more susceptible to chemotherapy, promoting more cell death by apoptosis.

Because CD20 is on all B cells, Rituxan® (rituximab) kills normal as well as cancer cells. However, patients can regenerate normal B cells from their own or transplanted blood stem cells.
Data
Font National Cancer Institute, http://www.cancer.gov/cancertopics/understandingcancer/targetedtherapies/htmlcourse/page4
Autor DesconegutUnknown author

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Public domain This image is a work of the National Institutes of Health, part of the United States Department of Health and Human Services, taken or made as part of an employee's official duties. As a work of the U.S. federal government, the image is in the public domain.
Please ensure that this image was actually created by the US Federal government. The NIH frequently uses commercial images which are not public domain.


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