Toxina Shiga Escherichia coli

La toxina Shiga Escherichia coli (en anglès:Shiga Toxine Escherichia Coli, STEC) és un bacteri productor de potents toxines[1] i responsable d'algunes intoxicacions alimentàries[2][3] causants de colitis hemorràgiques[4] i -en casos greus- de la síndrome hemolítica i urèmica,[5][6] la principal causa d'insuficiència renal aguda en nens petits.[7] Es coneixen múltiples soques del bacteri, no totes elles amb la mateixa virulència.[8][9] El seu reservori principal són els remugants,[10] encara que s'han registrat diversos casos d'infeccions humanes associades al contacte amb ocells, gossos o cavalls.[11]

Aquest microorganisme es coneix també sota altres noms, com enterohemorrhagic E. coli (EHEC),[12] Shiga-like toxin-producing E. coli (SLTEC o STEC),[13] hemolytic uremic syndrome–associated enterohemorrhagic E. coli (HUSEC) i verocytotoxin o verotoxin-producing E. coli (VTEC).[14]

Shiga fa referència a Kiyoshi Shiga[15] qui descobrí Shigella dysenteriae[16] una de les espècies que formen el gènere Shigella.[17]

ReferènciesModifica

  1. Melton-Celsa, AR «Shiga Toxin (Stx) Classification, Structure, and Function» (en anglès). Microbiol Spectr, 2014; 2 (2), pàgs: 24. PMID: 25530917. DOI: 10.1128/microbiolspec.EHEC-0024-2013. PMC: 4270005 [Consulta: 25 maig 2020].
  2. Vernozy-Rozand, C; Montet, MP; Berardin, M; Bavai, C; Beutin, L «Isolation and characterization of Shiga toxin-producing Escherichia coli strains from raw milk cheeses in France» (en anglès). Lett Appl Microbiol, 2005; 41 (3), pp: 235-241. ISSN 1472-765X. DOI: 10.1111/j.1472-765X.2005.01756.x. PMID: 16108913 [Consulta: 25 maig 2020].
  3. Rípodas Navarro, A; Fernández Moreira, D; Macho Martínez, M «Investigación de Escherichia Coli productor de toxinas Shiga (STEC) en carnes y derivados cárnicos» (en castellà). Sanid Mil, 2017 Jul-Set;, pp: 147-152. ISSN 1887-8571. DOI: 10.4321/s1887-85712017000300002 [Consulta: 25 maig 2020].
  4. Fiorito, P; Burgos, JM; Miyakawa, MF; Rivas, M; et al «Effect of Shiga toxin 2 on water and ion transport in human colon in vitro» (en anglès). Dig Dis Sci, 2000 Mar; 45 (3), pp: 480-486. ISSN 0163-2116. DOI: 10.1023/a:1005480720832. PMID: 10749321 [Consulta: 3 juny 2020].
  5. Decludt, B; Bouvet, P; Mariani-Kurkdjian, P; Grimont, F; Grimont, PA; Hubert, B; et al «Haemolytic uraemic syndrome and Shiga toxin-producing Escherichia coli infection in children in France» (en anglès). Epidemiol Infect, 2000 Abr; 124 (2), pp: 215-220. PMID: 10813145. DOI: 10.1017/s0950268899003623. PMC: 2810903 [Consulta: 25 maig 2020].
  6. Espié, E; Grimont, F; Mariani-Kurkdjian, P; Bouvet, P; Haeghebaert, S; Filliol, I; et al «Surveillance of hemolytic uremic syndrome in children less than 15 years of age, a system to monitor O157 and non-O157 Shiga toxin-producing Escherichia coli infections in France, 1996-2006» (en anglès). Pediatr Infect Dis J, 2008 Jul; 27 (7), pp: 595-601. ISSN 0891-3668. DOI: 10.1097/INF.0b013e31816a062f. PMID: 18520972 [Consulta: 25 maig 2020].
  7. Gerber, A; Karch, H; Allerberger, F; Verweyen, HM; Zimmerhackl, LB «Clinical course and the role of shiga toxin-producing Escherichia coli infection in the hemolytic-uremic syndrome in pediatric patients, 1997-2000, in Germany and Austria: a prospective study» (en anglès). J Infect Dis, 2002 Ag 15; 186 (4), pp: 493-500. ISSN 1537-6613. DOI: 10.1086/341940. PMID: 12195376 [Consulta: 3 juny 2020].
  8. Boerlin, P; McEwen, SA; Boerlin-Petzold, F; Wilson, JB; et al «Associations Between Virulence Factors of Shiga Toxin-Producing Escherichia Coli and Disease in Humans» (en anglès). J Clin Microbiol, 1999 Mar; 37 (3), pp: 497-503. PMID: 9986802. DOI: 10.1128/JCM.37.3.497-503.1999. PMC: 84443 [Consulta: 26 maig 2020].
  9. Bertin, Y; Boukhors, K; Pradel, N; Livrelli, V; Martin, C «Stx2 subtyping of Shiga toxin-producing Escherichia coli isolated from cattle in France: detection of a new Stx2 subtype and correlation with additional virulence factors» (en anglès). J Clin Microbiol, 2001 Set; 39 (9), pp: 3060-3065. PMID: 11526129. DOI: 10.1128/JCM.39.9.3060-3065.2001. PMC: 88297 [Consulta: 26 maig 2020].
  10. ACSA «E. coli productor de toxina Shiga (ECTS o STEC)». Departament de Salut, Generalitat de Catalunya, 2019; Set 2 (rev), pàgs: 3 [Consulta: 25 maig 2020].
  11. Larson, DG «Prevalence of shiga toxin-producing Escherichia coli in the Sacramento valley equine population -Tesi doctoral-» (en anglès). California State University, Sacramento, 2009; tardor, pàgs: 57 [Consulta: 26 maig 2020].
  12. Institut Pasteur «Enterohemorrhagic E. coli (EHEC)» (en anglès). Disease sheets, 2019; Set 16 (rev), pàgs: 8 [Consulta: 24 maig 2020].
  13. Beutin, L; Steinrück, H; Krause, G; Steege, K; et al «Comparative evaluation of the Ridascreen Verotoxin enzyme immunoassay for detection of Shigatoxin producing strains of Escherichia coli (STEC) from food and other sources» (en anglès). J Appl Microbiol, 2007 Mar; 102 (3), pp: 630-639. ISSN 1365-2672. DOI: 10.1111/j.1365-2672.2006.03139.x. PMID: 17309611 [Consulta: 25 maig 2020].
  14. Karch, H; Tarr, P; Bielaszewska, M «Enterohaemorrhagic Escherichia coli in human medicine» (en anglès). Int J Med Microbiol, 295, 6-7, 05-10-2005, pp: 405–418. ISSN 1438-4221. DOI: 10.1016/j.ijmm.2005.06.009. PMID: 16238016.
  15. Fresquet, JL «Kiyoshi Shiga (1871-1957)» (en castellà). Historiadelamedicina.org, 2002; Set, págs: 6 [Consulta: 25 maig 2020].
  16. ITIS «Shigella dysenteriae (Shiga, 1898) Castellani and Chalmers, 1919» (en anglès). Standard Report Page, 2020 Gen 17; 966038 (rev), pàgs: 2 [Consulta: 26 maig 2020].
  17. Strockbine, NA; Jackson, MP; Sung, LM; Holmes, RK; O'Brien, AD «Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1» (en anglès). J Bacteriol, 1988; Mar; 170(3), pp: 1116-1122. PMID: 2830229. DOI: 10.1128/jb.170.3.1116-1122.1988. PMC: 210880 [Consulta: 25 maig 2020].

BibliografiaModifica

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  • Groupe de travail «STEC». Bilan des connaissances relatives aux Escherichia coli producteurs de Shiga-toxines (STEC) (en francès). AFSSA, 2003; Abr, págs: 220 [Consulta: 25 maig 2020]. 
  • Douellou, Thomas. Pathogénicité des Escherichia coli producteurs de Shiga-toxines (STEC) des produits laitiers: diversité génétique et impact des globules gras du lait -Tesi doctoral- (en francès). Sciences agricoles. Université Blaise Pascal - Clermont-Ferrand, 2017; Feb NNT: 2016CLF22712, págs: 296 [Consulta: 25 maig 2020]. 
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